Our invention disclosures a biodosimeter and method of measurements a dose of radiation and/or biological-chemical substances absorbed by human or animal body, microbes, plants. The invention describes a multiparametric analysis system to evaluate biochemical and physical patterns related to a range of doses of radiation and/or biological-chemical substances following exposure of human body by radiation and/or biological-chemical substances. In our invention we also propose to use a method of plasmon enhancement by which intrinsic biomolecular targets within human body may increase their fluorescence QY close to unity, especially for the variety of biochemicals. The disclosed robust biodosimeter provides fast-response field applications to normal populations exposed to radiation and/or biological-chemical substances release, and to first-responders evaluating those normal populations.