The invention relates to compositions and methods for treating
hypercholesterolemia, including methods for increasing HDL cholesterol
levels, using a composition comprising an extract from the Ortanique
peel. The invention also relates to compositions and methods for treating
hypercholesterolemia, including methods for increasing HDL cholesterol
levels, using a composition comprising substantially similar amounts of
tetramethylscutellarein and nobiletin by weight and/or a composition
comprising substantially similar amounts of tetramethylscutellarein,
nobiletin, and tangeretin by weight.