A method for production of artificial skin by administering matrix metalloproteinase inhibitor or matrix metalloproteinase inhibitor and matrix protein production promoting agent. The matrix metalloproteinase inhibitor is N-hydroxy-2(R)-[[(4-methoxyphenyl)sulfonyl](3-picolyl)amino]-3-methylbuta- namide hydrochloride.

 
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> Method of drilling using invert emulsion drilling fluids

> Fast-drying aqueous compositions with hollow particle binders and traffic paints made therewith

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