This invention provides an e-learning system having a capability for authenticating the learner's ID via Internet with the learner's physical Bio-ID such as a fingerprint, an iris and/or a vein of the learner into the login process and additional periodic checking according to the instruction signal generated by the contents. Accordingly, once a learner successfully logs into his or her account, the computer will monitor each learner's progress on a lecture or an examination. Thus, the invention enable to operate a full online distance education from a single database for the worldwide learners, at each learner's own space and scheduling, anytime, anyplace, in any of the major languages selected by the learners and accurately account credit hours of each learner by the lectures and examination on demand for conferring a degree or to transfer the credit to the university where they will earn their degrees.