Method and device for interference cancellation. A radio access unit comprises a plurality of directionally separated antenna elements (41.sub.k, K=1, 2, . . . , L) for receiving signals transmitted by a plurality of remote units. From signals received by each of the antenna elements (41.sub.k) first weighing factors (g(1).sub.k) are determined (49), for optimally selecting signal of a first remote unit (52.sub.1). A first radio signal (s.sub.1) of the first communication unit (52.sub.1) is provided by weighing (44) the received signals using the first weighing factors (g(1).sub.k). For a further radio communication unit (52.sub.i) further weighing factors (g(i)k) are determined. A corrected further radio signal (s'.sub.i) is provided each time by subtracting (46) from the further radio signal (s.sub.i), previously obtained corrected radio signal (S'.sub.i-1, S'.sub.i-1, . . . ) weighed by the further weighing factors (g(i).sub.k), till a stop criterium has been satisfied.