Provided is a lysis method for cells or viruses, including: immobilizing a
metal-ligand complex on a solid support; and mixing the complex
immobilized on the support with a cell or virus solution. According to
the lysis method, by immobilizing a chemical on a solid support to
perform cell lysis, the dilution problem according to the addition of a
cell lysis solution can be resolved and a separate process of removing
the chemical is not required so as to reduce the steps upon LOC
implementation. In addition, since a variety of solid supports, such as
chips, beads, nanoparticles etc. can be used, cell lysis apparatuses of
various forms can be fabricated.