Methods and systems for contacting a crude feed with one or more catalysts produces a total product that include a crude product are described. The crude product is a liquid mixture at 25.degree. C. and 0.101 MPa. One or more properties of the crude product may be changed by at least 10% relative to the respective properties of the crude feed. The produced crude product may include sulfur, residue, Micro-Carbon Residue, C.sub.5 asphaltenes, or mixtures thereof.