A process is disclosed for the manufacture of CF.sub.3CH.sub.2CHF.sub.2 and CF.sub.3CHFCH.sub.2F. The process involves (a) reacting hydrogen fluoride, chlorine, and at least one halopropene of the formula CX.sub.3CCl.dbd.CClX (where each X is independently F or Cl) to produce a product including both CF.sub.3CCl.sub.2CClF.sub.2 and CF.sub.3CClFCCl.sub.2F; (b) reacting CF.sub.3CCl.sub.2CClF.sub.2 and CF.sub.3CClFCCl.sub.2F produced in (a) with hydrogen to produce a product including both CF.sub.3CH.sub.2CHF.sub.2, and CF.sub.3CHFCH.sub.2F; and (c) recovering CF.sub.3CH.sub.2CHF.sub.2 and CF.sub.3CHFCH.sub.2F from the product produced in (b). In (a), the CF.sub.3CCl.sub.2CF.sub.3 and CF.sub.3CClFCClF.sub.2 are produced in the presence of a chlorofluorination catalyst including (i) a crystalline alpha-chromium oxide where at least 0.05 atom % of the chromium atoms in the alpha-chromium oxide lattice are replaced by divalent copper, and/or (ii) a chromium-containing composition of (i) which has been treated with a fluorinating agent.