In a method for monitoring a control loop in a process plant, process gain data associated with a control loop may be collected. The collected process gain data may be used to determine an expected process gain behavior. For example, expected values of a process variable for given values of a load variable may be determined. As another example, expected changes in a process variable for given changes in a load variable may be determined. Then, during operation of the control loop, the process gain may be monitored. If the monitored process gain substantially deviates from the expected behavior, this may indicate an abnormal situation associated with the control loop.