Systems and methodologies are described that facilitate efficient power control command management in a wireless communication environment. As described herein, techniques can be utilized by a Node B and/or other network access point to compensate for differences between uplink slot boundaries and a power control command combining period associated with the uplink slot. For example, the timing of Transmitter Power Control (TPC) bit transmission can be altered as described herein such that, if a given cell or cell sector is associated with a radio link set of size 2 or greater and a TPC timing offset of size 2 or less, TPC command information can be buffered and/or otherwise delayed to a slot following the slot in which corresponding channel measurements are obtained in order to prevent efficiency loss associated with combining TPC bits of inverse polarity corresponding to multiple disparate slots.