A multi-ply absorbent sheet of cellulosic fiber with continuous outer surfaces is provided an absorbent core between the outer surfaces. The absorbent core includes a non-woven fiber network having: (i) a plurality of pileated fiber enriched of relatively high local basis weight interconnected by way of (ii) a plurality of lower local basis weight linking whose fiber orientation is biased along the direction between pileated interconnected thereby, and (iii) a plurality of fiber-deprived cellules between the fiber enriched and linking regions, also being characterized by a local basis weight lower than the fiber enriched regions. The cellules provide a sponge-like internal structure of low fiber density regions.

 
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> Methods for treatment of insulin-like growth factor-1 (IGF-1) deficiency comprising administration of IGF-1 and growth hormone

> Creating and maintaining a gas cap in tar sands formations

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