An osteochondral repair implant is provided, comprising a tissue scaffold
configured to allow growth of at least bone and/or cartilage and to fit
within at least a portion of an osteochondral hole, the tissue scaffold
comprising one or more recesses and/or projections; and a biodegradable
carrier containing a growth factor, the biodegradable carrier being
placed in and/or around the recesses and/or projections of the tissue
scaffold and reduce compression of the biodegradable carrier by the
tissue scaffold. In some embodiments, methods for repairing an
osteochondral defect are provided that utilize an osteochondral plug and
a biodegradable carrier containing a growth factor.