The present invention relates to water-soluble solid pharmaceutical compositions and their solutions in aqueous solvents, said compositions containing a) as an active ingredient a finely dispersed large surface area amorphous preferably lyophilized taxoid such as paclitaxel or docetaxel, their salts or their polymorphic hydrates or solvates such as solvates formed with ethanol and b) finely dispersed large surface area amorphous preferably lyophilized acetyl-.gamma.-cyclodextrin or hydroxy-propyl-.beta.-cyclodextrin (cyclodextrin) whereby the weight ratio of said taxoid:said cyclodextrin ranges between 1:25 and 1:400; c) and optionally other water-soluble auxiliary materials usual in pharmaceuticals for parental purposes.