A noninvasive in vivo measuring system and a noninvasive in vivo measuring method are provided. In the noninvasive in vivo measuring system, a Raman-fluorescence measuring unit measures blood sugar concentration, which is measured using Raman spectra before and after applying a pressure on a finger, and outputs a final blood sugar level by correcting the blood sugar concentration measurement according to a Hemoglobin (Hb) concentration measured by an Hb measuring unit.