The invention relates to a novel group of compounds of Formula (I) or a
salt thereof: ##STR00001## wherein R.sup.1, R.sup.2, R.sup.3, n, A and
HET-1 are as described in the specification, which may be useful in the
treatment or prevention of a disease or medical condition mediated
through glucokinase (GLK) such as type 2 diabetes. The invention also
relates to pharmaceutical compositions comprising said compounds, methods
of treatment of diseases mediated by GLK using said compounds and methods
for preparing compounds of Formula (I).