Formed compositions for application to a bone surface of a human or animal
subject, comprising: a bone material; and a carrier comprising denatured
demineralized bone, where the composition is formed into a shape suitable
for administration to the bone. Methods are provided for making formed
compositions for application to a bone surface of a human or animal
subject comprise mixing a demineralized bone and water; heating the
mixture to form a carrier; mixing the carrier with bone to form a
moldable composition; and molding the moldable composition to produce a
formed composition. Several apparatuses are provided in which to hydrate
the formed bone composition. Methods of hydrating a formed bone
composition are also provided.