The present invention is directed to a waveguide sensor as well as to an evanescent field induced evanescent field induced sensor system for use in diagnostic housing and an integrated waveguide sensor comprising: a waveguide layer,--capture compounds applied on the upper surface of said waveguide layer for 5 specific bonding to target substances,--a cladding layer surface of said waveguide layer,--a filter which is transmitting for luminescent radiation while absorbs and/or reflects radiation of excitation radiation, wherein the filter is arranged below the lower 10 surface of said cladding layer, at least one detector for sensing luminescent radiation, wherein the detector is arranged below the lower surface of said filter, a substrate that is connected with the detector and comprises the electrical interface of said detector; wherein 15 between the upper surface of the waveguide layer and along at least a lower surface section of the housing a channel is formed for receiving a fluidic probe; and the luminescent radiation is generated by luminescent tag bound to target substances as a result of their excitation by the evanescent field. This provides an improved sensitivity of the evanescent field induced sensor 20 system.