The present invention generally provides a rapid efficient method for
analyzing polymorphic or biallelic markers, and arrays for carrying out
these analyses. In general, the methods of the present invention employ
arrays of oligonucleotide probes that are complementary to target nucleic
acids which correspond to the marker sequences of an individual. The
probes are typically arranged in detection blocks, each block being
capable of discriminating the three genotypes for a given marker, i.e.,
the heterozygote or either of the two homozygotes. The method allows for
rapid, automatable analysis of genetic linkage to even complex polygenic
traits.