Antisense compounds, compositions and methods are provided for modulating
the expression of superoxide dismutase 1, soluble. The compositions
comprise antisense compounds, particularly antisense oligonucleotides,
targeted to nucleic acids encoding superoxide dismutase 1, soluble.
Methods of using these compounds for modulation of superoxide dismutase
1, soluble expression and for treatment of diseases associated with
expression of superoxide dismutase 1, soluble are provided.