An antifreeze glycoprotein comprising at least one C-linked saccharide according to the following general formula: ##STR00001## wherein X is nitrogen, sulfur, carbon or (CR.sup.1R.sup.2).sub.nS.dbd.O wherein n is 0, 1, 2 or 3, Y is carbon, nitrogen, sulfur or oxygen, R.sup.1 is hydrogen, methyl, fluorine, a carbohydrate, or a hydroxy chain, R.sup.2 is hydrogen, methyl, fluorine, a carbohydrate or a hydroxy chain, R.sup.3 to R.sup.6 independently represent an alkyl chain, a hydroxy group, a dimethyl sulfoxy group, a carbohydrate or an ether, R.sup.7 is ornithine, lysine, an alkyl chain, a pyridyl group or a heterocycle; and R.sup.8 is hydrogen, fluorine a carbohydrate or a hydroxy or methoxy group. Such antifreeze glycoprotein analogues are useful recrystallization inhibitors and may be used as a cryoprotectant for tissue preservation and transplantation, improving the texture of processed frozen food and frozen meats, frostbite protection, crop protection, and green alternatives for land vehicle antifreeze and aircraft de-icing.