A method of providing general anesthesia to an organism that improves surgical outcome by controlling a psychic and a somatic surgical stress before, during, and after a surgical procedure by preventing a pathological elevation of Factor VIII in the blood of the organism, comprising the steps of controlling the psychic stress in the organism by administering to the organism an anesthetic or hypnotic agent; controlling the somatic stress by administering to the organism an opioid and/or lidocaine; maintaining a normal body temperature of the organism; minimizing a non-surgical stress stimuli; and allowing a mild hypercarbia to support a respiratory drive in the presence of an opioid dosage. The method may further comprise the step of giving additional doses of an opioid as necessary to prevent sympathetic nervous system activation.