The present invention relates to the field of radiographic examination and radioactive material inspection, and provides a system and a method capable of simultaneous radiographic examination and radioactive material inspection. The system comprises a radiographic examination system and a radiation monitor; wherein the radiographic examination system comprises an accelerator and a synchronization controller, and the radiation monitor comprises a detector, a front end circuit, a signal transmission controller, a data collecting, analyzing and processing computer, an alarm device and so on. The present invention combines the radiographic examination system and the radiation monitor tightly so that the radioactive material inspection can be executed while the radiographic examination is performed, thereby the examination efficiency is improved and the occupied area of the system is reduced.