The invention provides a novel herbal formulation useful as local anesthetic in topical surgical operations, nerve block conduction, extradural and infiltration anesthesia. Formulation(s) comprises of extract(s) of Spilanthus calva and Spilanthus oleraceae with Gymnema sylvestre, Urtica dioica and Piper longum. The formulation can be used as topical application as ointment or spray or cream.