The invention relates to a method of producing an agglomerate of drug and
solid binder. The process involves producing individual agglomerate
particles and then converting the convertible amorphous content of same,
following agglomeration, by the application of, for example, moisture.
Agglomerates capable of conversion as well as the finished agglomerates
and oral and nasal dosing systems including same are also contemplated.
The process produces agglomerates which are rugged but which will produce
an acceptable fine particle fraction during dosing.