Systems and methods are provided for generating and evaluating a plurality of courses of action (COAs) for a problem of interest having an associated set of problem characteristics. A case based reasoner generates an initial set of courses of action according to the associated problem characteristics. Each course of action includes a plurality of COA packages and a set of associated fitness parameters. A genetic algorithm refines the initial set of courses of action according to a set of global influence values to produce at least one optimized course of action. A user interface allows a user to adjust at least one value from the set of global influence values and the set of fitness parameters associated with each optimized course of action.