The present invention relates to a compound of formula (I), or a
pharmaceutically acceptable salt thereof, wherein Z is OR.sup.1 or
NR.sup.1R.sup.2 wherein each of R.sup.1 and R.sup.2 is independently H,
or a hydrocarbyl group; X is an alkylene, alkenylene, or alkynylene
group, each of which may be optionally substituted by one or more
substituents selected from alkyl, COOH, CO.sub.2-alkyl, alkenyl, CN,
NH.sub.2, hydroxy, halo, alkoxy, CF.sub.3 and nitro; Y is a polar
functional group selected from OH, NO.sub.2, CN, COR.sup.3, COOR.sup.3,
NR.sup.3R.sup.4, CONR.sup.3R.sup.4, SO.sub.3H, SO.sub.2--R.sup.3,
SO.sub.2NR.sup.3R.sup.4 and CF.sub.3, where each of R.sup.3 and R.sup.4
is independently H or a hydrocarbyl group; A is an aryl or heteroaryl
group, each of which may be optionally substituted; and B is (CH2).sub.n
where n is 0, 1, 2, 3, 4 or 5; with the proviso that: (i) when A is
phenyl, n is 0, and Z is OH, X--Y is other than
meta-C.ident.--C--(CH.sub.2).sub.2CO.sub.2H,
meta-C.ident.--C--(CH.sub.2).sub.2OH,
meta-C.ident.C--(CH.sub.2).sub.2CO.sub.2Me,
meta-(CH.sub.2).sub.4CO.sub.2H, ortho-CH.sub.2CO.sub.2H,
ortho-(CH.sub.2).sub.2CO.sub.2H and ortho-(CH.sub.2).sub.4CO.sub.2H; and
(ii) when A is phenyl, n is 0, and Z is OMe, X--Y is other than
meta-C.ident.C--(CH.sub.2).sub.4OH. Further aspects of the invention
relate to the use of such compounds in the preparation of a medicament
for the treatment of a muscular disorder, a gastrointestinal disorder, or
for controlling spasticity or tremors.