An orthopedic insole consists of a hollow foothold having flexible walls and containing granular filling. The upper surface of the orthopedic insole is typically molded to conform the anatomical features of a regular human foot. The granular filling contained in the lumen of the foothold and a rigid segment of its bottom wall provide for adapting the curvature angles of the top surface of the foothold to a specific pattern of the foot of a user. A user can typically make a selection from a variety of ready-made insoles having standard sizes which suit his needs. The adaptable orthopedic insoles of the invention are accommodated to common shoes and sandals, boots that are suitable for heavy work, walking, running, and or fashionable or mode shoes.