A novel crystalline form of
3-{[5-(azetidin-1-ylcarbonyl)pyrazin-2-yl]oxy}-5-[(1-methylethyl)oxy]-N-1-
H-pyrazol-3-ylbenzamide is described in the specification. This compound
is a glucokinase (GLK or GK) activator and useful as a pharmaceutical
agent in the treatment or prevention of a disease or medical condition
mediated through GLK, leading to a decreased glucose threshold for
insulin secretion. Processes for the manufacture of the crystalline form,
pharmaceutical compositions comprising the crystalline form and the use
of the crystalline form in medical treatment are also described.