Compounds of Formula I and Formula II: (wherein n, R.sup.1, R.sup.2,
R.sup.3, R4, R.sup.5, R.sup.6, R.sup.7, R.sup.8, R.sup.9, R.sup.10,
R.sup.15, R.sup.16, R.sup.17, R.sup.18, R.sup.19, R.sup.24, R.sup.25,
R.sup.26, R.sup.27, R.sup.28, R.sup.29, R.sup.30, R.sup.33, R.sup.34,
R.sup.35, R.sup.36, R.sup.37, R.sup.38, A, j, k, m, n, X, Y and Z are as
defined herein) which are modulators of chemokine receptor activity and
are useful in the prevention or treatment of certain inflammatory and
immunoregulatory disorders and diseases, allergic diseases, atopic
conditions including allergic rhinitis, dermatitis, conjunctivitis, and
asthma, as well as autoimmune pathologies such as rheumatoid arthritis
and atherosclerosis. The invention is also directed to pharmaceutical
compositions comprising these compounds and the use of these compounds
and compositions in the prevention or treatment of such diseases in which
chemokine receptors are involved. ##STR00001##