In one embodiment, a method is provided for lowering PPAR-Gamma in a mammal. The method comprises administering a composition containing an effective amount of Irvingia gabonensis seed to a mammal to reduce PPAR-Gamma levels in the mammal. In other embodiments, among other things, methods are provided for reducing triglyceride levels, inhibiting or reducing G3PDH activity, reducing body weight and increasing adiponectin levels in a mammal by administering Irvingia gabonensis.

 
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> IRVINGIA GABONENSIS TO TREAT AND PREVENT METABOLIC SYNDROME AND REDUCE TOTAL CHOLESTEROL, LDL CHOLESTEROL, BLOOD GLUCOSE, C-REACTIVE PROTEIN, AND LEPTIN LEVELS AND INCREASING ADIPONECTIN LEVELS

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