The electronic seal with radio frequency identification of the present invention comprises a lock cylinder and a lock latching plug to form an integral lock portion, which having RF chip, RF antenna with associated electric circuits, conductors and RF chip, wherein the lock cylinder comprises a metal lower antenna tube and a metal upper antenna tube to form each opposite pole of the dipole antenna. With relay conductor and propagating conductor being built in the central hollow space to connect with RF antenna and RF chip respectively, the RFID system is activated if lock cylinder and lock latching plug joint together.