Associating data source information with sampled runtime events allows identification of system components related to the sampled runtime events. Code can be optimized from the perspective of system components and for various architectures. A system provides a data source indication. The system associates the data source indication with a corresponding instruction instance. The instruction instance is related to a sampled runtime event, and the sampled runtime event is associated with the data source indication. The data source information and associated sampled runtime event can be supplied for profiling code.