The invention provides a composition useful for making oral dosage forms
capable of dissolving in the mouth in less than 40 seconds without the
need for a conventional super disintegrant and having a friability of
less than 1%; wherein the composition includes liquiflash particles and
an excipient mass. A preferred excipient mass according to the invention
contains a directly compressible inorganic salt; a cellulose derivative
or a combination of a directly compressible inorganic salt and a
cellulose derivative. Preferably, the liquiflash particles and the
excipient mass are combined in proportions such that the active
ingredient remains substantially within the microspheres when the
composition is compressed to obtain a dosage form having a hardness of 20
to 50 N. The compositions of the invention allow for the fabrication of
oral dosages having improved hardness and friability.