The invention is directed to methods and compositions for inhibiting caspase-independent apoptosis. In particular, methods and compositions for inhibiting Omi/HtrA2 activity, as well as method for identifying other inhibitors of Omi/HtrA2. Also disclosed are Omi/HtrA2 specific substrates and methods for identifying other substrates of Omi/HtrA2.

 
Web www.patentalert.com

< IDO inhibitors and methods of use

< Non-nucleoside reverse transcriptase inhibitors

> Arylvinylazacycloalkane compounds and methods of preparation and use thereof

> Heterocyclic antiviral compounds
~ 00606