The present invention provides a method for producing mesenchymal cells
for production of mesenchymal cells for formation of a tooth, the method
comprising: culturing totipotent stem cells in the presence of a
differentiation inducer to produce a cell population after
differentiation induction treatment, the cell population containing
CD44-positive and CD29-positive cells or CD44-positive and CD
106-positive cells; and selecting, from the cell population after the
differentiation induction treatment, the CD44-positive and CD29-positive
cells or CD44-positive and CD 106-positive cells as the mesenchymal cells
for the formation of the tooth. The present invention also provides a
method for producing a tooth comprising: positioning, in a support
carrier capable of retaining cells in a state of contacting therewith, a
first cell mass substantially consisting of only either one of
mesenchymal cells and epithelial cells and a second cell mass
substantially consisting of only the other one of the mesenchymal cells
and epithelial cells, the first and second cell masses being not mixed
with each other but made to closely contact with each other; and
culturing the first and second cell masses; wherein the mesenchymal cells
comprise the mesenchymal cells for the formation of the tooth.