A method is disclosed for obtaining the location of a landmark in an MR
image of a brain. In a first step, a region of interest in a plane within
the MR image containing the landmark is defined. In a second step, the
ROI is binarised into foreground and background voxels based on at least
one threshold selected using anatomical knowledge. In a third step a set
of object voxels is identified from the foreground voxels, excluding
voxels which were only classified as object due to proximity of cortical
and non-cortical structures. This can be done by morphological processing
which reclassifies voxels which may have been incorrectly classified as
object, followed by restoring voxels due to the partial volume effect
and/or morphological erosion/opening. In a fourth step, an automatic
process is then carried out to identify one or more landmarks in the
modified binarised image.