There is provided methods and systems for optical imaging in a turbid medium that combine continuous wave (CW) and time domain (TD) approaches to substantially increase robustness of optical imaging as well as to reduce acquisition times associated with the TD approach. In one aspect, a method is provided that uses CW measurements to scale the values of a temporal point spread function (TPSF) to avoid physical unit mismatch problems. In another aspect, both CW and TD measurements are synergistically combined to estimate optical properties of the medium used in image reconstruction. Optical systems capable of realizing these methods are also provided.