A method, system, graphical user interface, and apparatus are provided for performing a patient management function providing parameter data for delivering a therapeutic signal. A first electrical signal comprising a first therapy parameter is applied to a portion of a patient's body for providing a therapy. At least one patient parameter relating to an effect of applying the first electrical signal is acquired. A second therapy parameter for defining a second electrical signal to provide a therapy is determined in response to the patient parameter. The second therapy parameter is displayed on an external device. An input signal for defining the second electrical signal is received. The input signal includes a signal indicative of the whether the second therapy parameter was accepted or not.

 
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> Upstream control elements of the proopiomelanocortin gene and their use

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