A method for manufacturing a multi-resin composite article is provided. The method comprises providing at least one fiber preform in a mold; injecting a plurality of resins into the at least one fiber preform at a plurality of locations on the at least one fiber preform; and forming at least one transition region along a mutual contact surface between the resins. Each of the at least one transition regions is defined by a gradual transition in composition from one of the resins to another of the resins. A multi-resin composite article is also provided. The article comprises: at least one fiber preform; a plurality of resins, wherein the at least one fiber preform is infused with the resins; and at least one transition region extending along a mutual contact surface between respective ones of the resins. A system for manufacturing such a multi-resin composite article is also provided.