A natural formulation of compounds that would to modulate inflammation is disclosed. The formulation would also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively in target cells. The compositions containing at least one fraction isolated or derived from hops.

 
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> Method of screening for a compound using guanosine triphosphate (GTP)-binding protein-coupled receptor protein, BG37

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