A seal for a valve for use in a pharmaceutical dispensing device, which
seal is formed from an elastomeric composition comprising: (a) an
isobutylene polymer or co-polymer thereof; (b) a cross-linking agent for
the isobutylene polymer or co-polymer thereof; and (c)) an accelerator
for the cross-linking agent, wherein the accelerator includes a
polysulphide compound derived from a substituted dithiocarbonic acid or
derivative thereof.