A multizone RF read/write system for conducting transactions with vehicles traveling at high speeds. A first RF read zone is created, preferably by use of a first gantry that extends over at least one lane and contains at least one RF source that creates a large powerful RF read zone for reading or reading and writing to a transponder on a passing vehicle. Additional RF read zones arranged in tandem with the first RF read zone are created by at least one additional RF source that is located on an additional gantry extending over at least one lane, or located on the first gantry. Accordingly, multiple RF read zones are created to conduct transactions with passing vehicles. In one aspect, the multiple RF read zones can be used to ensure that tolling transactions with a single vehicle are more likely to be completed and have a higher degree of accuracy. In another aspect, the multiple RF read zones each employ a different RF technology so that multiple types of RF toll tags can be read and written.