A novel cytokine designated TRAIL induces apoptosis of certain target cells, including cancer cells and virally infected cells. Isolated DNA sequences encoding TRAIL are disclosed, along with expression vectors and transformed host cells useful in producing TRAIL polypeptides. Antibodies that specifically bind TRAIL are provided as well.

 
Web www.patentalert.com

< Method for identifying motifs and/or combinations of motifs having a boolean state of predetermined mutation in a set of sequences and its applications

< Catheter insertion device with automatic safety barrier

> Anti-CD71 monoclonal antibodies and uses thereof for treating malignant tumor cells

> Methods of inhibiting human immunodeficiency virus infection through the administration of synergistic combinations of anti-CCR5 monoclonal antibodies, fusion inhibitors, and CD4-GP120 binding inhibitors
~ 00615