It is an objective of the present invention to identify SPARC
protein-derived peptides that are able to induce human killer T cells and
helper T cells having cytotoxic activity to tumors, and to provide a
means for carrying out a tumor immunotherapy of patients with various
types of cancers overexpressing SPARC. The present invention provides a
peptide of any of the following: (A) a peptide which consists of the
amino acid sequence as shown in any one of SEQ ID NOS: 1 to 3; or (B) a
peptide which consists of an amino acid sequence comprising a
substitution or addition of one or several amino acids with respect to
the peptide consisting of the amino acid sequence as shown in any one of
SEQ ID NOS: 1 to 3, and which has capacity to induce cytotoxic (killer) T
cells.