An intuitive real spatial aiming-based system and identification and communication methods are presented. The intuitive real spatial aiming-based system includes aiming device, target devices and an indoor location-based service server. The aiming device includes a mobile computer or a Personal Digital Assistant (PDA), which is provided with a first wireless communication tool, a first location tracking sensor, and an electronic compass having a magneto resistive sensor for detecting a directions. The target devices each includes a fixed computer, a home appliance, a PDA, or a mobile communication terminal, which is selectively provided with second wireless communication tool and a second location tracking sensor. The indoor location-based service server tracks the indoor locations and coordinates the aiming device and the target devices in real time. To tolerate sensor's error, an angle-based target region, a width-based target region, and a combination of the two regions presented.