An isolated antibody that specifically binds to an extracellular domain of human DLL4 and affects growth of a tumor comprising cancer stem cells is described. Also described is a method of treating cancer comprising administering a therapeutically effective amount of an anti-DLL4 antibody.

 
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< Ligand-regulable transactivation systems, methods of use thereof, methods of detecting estrogen receptor ligands, and methods of differentiating estrogen receptor ligand agonists and antagonists

< ANIMAL MODEL

> Antibodies that bind to a member of the IL-6/G-CSF/MGF family

> DISCONTINUOUS METHODS OF TREATING CANCER
~ 00620