Compounds of general formula (I) ##STR00001## wherein W is chloro or
fluoro; R.sup.1 is phenyl optionally substituted with one or more
substituents, selected from halo, --CN, --C.sub.1-C.sub.6 alkyl,
--SOR.sup.3, --SO.sub.2R.sup.3, --SO.sub.2N(R.sup.2).sub.2,
--N(R.sup.2).sub.2, --NR.sup.2C(O)R.sup.3, --CO.sub.2R.sup.2,
--CONR.sup.2R.sup.3, --NO.sub.2, --OR.sup.2, --SR.sup.2,
--O(CH.sub.2).sub.pOR.sup.2, or
--O(CH.sub.2).sub.pO(CH.sub.2).sub.qOR.sup.2 wherein each R.sup.2 is
independently hydrogen, --C.sub.1-C.sub.6 alkyl, --C.sub.3-C.sub.8
cycloalkyl, aryl or heteroaryl; each R.sup.3 is independently,
--C.sub.1-C.sub.6 alkyl, --C.sub.3-C.sub.8 cycloalkyl, aryl or
heteroaryl; p and q are each independently an integer from 1 to 3; and
R.sup.4 is hydrogen, C.sub.1-C.sub.6 alkyl, C.sub.1-C.sub.6 alkyl
substituted with aryl, aryl,
(CH.sub.2).sub.mOC(.dbd.O)C.sub.1-C.sub.6alkyl,
((CH.sub.2).sub.mO).sub.nCH.sub.2CH.sub.2X,
(CH.sub.2).sub.mN(R.sup.5).sub.2 or
CH((CH.sub.2).sub.mO(C.dbd.O)R.sup.6).sub.2; m is 1 or 2; n is 1-4; X is
OR.sup.5 or N(R.sup.5).sub.2; R.sup.5 is hydrogen or methyl; and R.sup.6
is C.sub.1-C.sub.18 alkyl; and their pharmaceutically acceptable salts,
hydrates, solvates, complexes or prodrugs are useful in orally
administrable compositions for the treatment of allergic diseases such as
asthma, allergic rhinitis and atopic dermatitis.
