Fused heterocyclic compounds are disclosed that have formula 1: ##STR00001## where A, B, L, N, R.sup.1, R.sup.3, R.sup.4', Y and Z are as defined herein. The compounds and pharmaceutical compositions thereof are useful for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, cognitive disorders, anxiety, depression, and others.

 
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< Benzoisoindole derivatives and their use as EP4 receptor ligands

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> Bead for enantiomeric isomer resolution and process for producing the same

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