The inventors have cloned and expressed the chemokine-like genes from MCV type 1 and the closely related MCV type 2 in order to determine a potential role for these proteins in the viral life cycle. These are the first viral chemokines that have been shown to antagonize the chemotactic activity of human chemokines and the first viral chemokines that have been shown to have inhibitory activity on human hematopoietic progenitor cells. Methods and compositions for exploiting these proteins are disclosed herein.

Los inventores se han reproducido y expresado chemokine-como genes a partir MCV del tipo 1 y MCV del tipo de cerca relacionado 2 para determinar un papel potencial de estas proteínas en el ciclo vital viral. Éstos son los primeros chemokines virales que se han demostrado para poner la actividad en contra quimiotáctica de los chemokines humanos y de los primeros chemokines virales que se han demostrado para tener actividad inhibitoria en las células hematopoietic humanas del progenitor. Los métodos y las composiciones para explotar estas proteínas se divulgan adjunto.

 
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> Cardiac glycosides and their aglycone derivatives treat complications of diabetes

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