An automated analyzer for performing multiple diagnostic assays
simultaneously includes multiple stations, or modules, in which discrete
aspects of the assay are performed on fluid samples contained in reaction
receptacles. The analyzer includes stations for automatically preparing a
specimen sample, incubating the sample at prescribed temperatures for
prescribed periods, preforming an analyte isolation procedure, and
ascertaining the presence of a target analyte. An automated receptacle
transporting system moves the reaction receptacles from one station to the
next. The analyzer further includes devices for carrying a plurality of
specimen tubes and disposable pipette tips in a machine-accessible manner,
a device for agitating containers of target capture reagents comprising
suspensions of solid support material and for presenting the containers
for machine access thereto, and a device for holding containers of
reagents in a temperature controlled environment and presenting the
containers for machine access thereto. A method for performing an
automated diagnostic assay includes an automated process for isolating and
amplifying a target analyte. The process is performed by automatically
moving each of a plurality of reaction receptacles containing a solid
support material and a fluid sample between stations for incubating the
contents of the reaction receptacle and for separating the target analyte
bound to the solid support from the fluid sample. An amplification reagent
is added to the separated analyte after the analyte separation step and
before a final incubation step.